Program Agenda

Monday, September 23, 2019
4:00pm Guest Arrival and Check-in at Sheraton Lake Buena Vista (Hotel check-in is at 3pm.)
5:00pm - 8:00pm Registration Open
5:00pm - 7:00pm Poster Presenters and Exhibitors Set Up Displays
7:00pm - 8:00pm Welcome Reception
8:00pm - 9:00pm

Keynote Address - Majestic Palm ABC

Roland Baron, Harvard Medical School and Harvard School of Dental Medicine, Boston, MA, USA
Osteocytic Osteolysis Revisited: Does It Happen, What Does It Do, and How to Measure It?

Tuesday, September 24, 2019
7:30am - 8:30am Morning Refreshments in Majestic Palm EFG
7:30am - 5:30pm Registration Open
7:30am - 5:00pm Posters on Display
Session 1 [8:30am - 10:00am]
Session Title Bone Remodeling: Coupling of Bone Resorption and Formation
Moderator D. Rick Sumner, Rush University Medical Center, Chicago, IL, USA
8:30am Thomas L. Andersen, University of Southern Denmark, Odense, Denmark
Bone Remodeling and Bone Loss During Aging: New Lessons from Cortical Bone
9:00am Christina M. Andreasen, University of Southern Denmark, Odense, Denmark
Assessment of the Intracortical Vascular Network and its Modulation Within Intracortical BMUs in Human Bone
9:15am Jean-Marie Delaisse, University of Southern Denmark, Odense, Denmark
Proper Evaluation of Bone Remodeling Requires Attention for the Reversal Phase
9:30am Lara Sattgast, Oregon State University, Corvallis, OR, USA
Effects of Ethanol Consumption on Intracortical Bone Remodeling and Biochemical Markers of Bone Turnover in Young Adult Male Cynomolgus Macaques
9:45am Brittany M. Wilson, Rush University Medical Center, Chicago, IL, USA
Remote Bone Loss After Implant Surgery in a Rat Model
10:00am - 10:30am Refreshment Break and Networking in Majestic Palm EFG
Session 2 [10:30am - 12 noon]
Session Title Influence of Biomechanics on Bone Development and Regeneration
Moderator Sara H. Windahl, Karolinska Institutet, Huddinge, Sweden
10:30am Joel D. Boerckel, University of Pennsylvania, Philadelphia, PA, USA
Recapitulating Bone Development for Regeneration
11:00am Ariane C. Scheuren, ETH, Zurich, Switzerland
Loading Frequency Affects Bone Adaptation in Mouse Caudal Vertebrae as Assessed by Longitudinal Micro-CT and Dynamic In Vivo Morphometry
11:15am Lei Zhao, Hokkaido University, Sapporo, Japan
Mineral-Tissue Mechanical Relationship in Biomimetically Remineralized Bovine Bone Tissue
11:30am Francesca Salamanna, IRCCS-Istituto Ortopedico Rizzoli, Bologna, Italy
Natural Wood Transformed Into Large 3-D Hydroxyapatite (HA) Biomimetic Scaffold for Segmental Bone Reconstruction
11:45am Maria Sartori, IRCCS-Instituto Ortopedico Rizzoli, Bologna, Italy
Evaluation of Bone Regeneration of a Critical Bone Defect Treated with a Magnetic Scaffold and Local Delivery of Vascular Endothelial Growth Factor
12 noon- 1:30pm Lunch and Poster Viewing
(Poster Presenters are to be stationed at their poster displays from 12:45pm - 1:30pm)
Session 3 [1:30pm – 3:00pm]
Session Title Marrow Fat and Bone Function
Moderator Urszula T. Iwaniec, Oregon State University, Corvallis, OR, USA
1:30pm William P. Cawthorn, University of Edinburgh, Edinburgh, Scotland, UK
Endocrine and Metabolic Functions of Bone Marrow Adipose Tissue
2:00pm Urszula T. Iwaniec, Oregon State University, Corvallis, OR, USA
Voluntary Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity
2:15pm Samantha Costa, Maine Medical Center Research Institute, Scarborough, ME, USA
Sclerostin Antibody Normalizes Decreased Trabecular Bone and Increased Bone Marrow Adipose Tissue Caused by Whole-Body Irradiation in Mice
2:30pm Urszula T. Iwaniec, Oregon State University, Corvallis, OR, USA
Propranolol Antagonizes the Adaptive Response of Bone Marrow Adipose Tissue to Cold Temperature Stress Induced by Room Temperature Housing
2:45pm Danielle E. Whittier, University of Calgary, Calgary, AB, Canada
Heterogeneous Bone Loss Measured as Void Space in the Metaphyseal Region Alters Which Microarchitectural Predictors are Associated With Hip Fracture Risk
3:00pm - 3:30pm Refreshment Break and Networking in in Majestic Palm EFG
Session 4 [3:30pm - 5:00pm]
Session Title Single Cell and Subcellular Imaging in Bone
Moderator Jillian Cornish, University of Auckland, Auckland, New Zealand
3:30pm Erica L. Scheller, Washington University School of Medicine, Saint Louis, MO, USA
Single Cell Imaging of Nerves and Fat From Bone to Brain
4:00pm Sarah L. Dallas, University of Missouri Kansas City, Kansas City, MO, USA
Live Cell and Intravital Imaging of Osteoclasts and the Fate of Osteocytes Following Osteoclast Resorption
4:15pm Leeann Louis, University of California, Berkeley, CA, USA
Reproductive Behavior Leads to Massive Restructuring of Bird Bone
4:30pm Adriana L. Carvalho, Maine Medical Center Research Institute, Scarborough, ME, USA
Morphine Treatment Reduces Trabecular Bone Volume Fraction and Impairs Cortical Bone Expansion in Male Mice
4:45pm Frank C. Ko, Rush University Medical Center, Chicago, IL, USA
Contribution of Trabecular Bone Properties to Implant Fixation Strength in Rats
5:00pm Sessions Conclude for the Day; Dinner on your own (Disney Springs Excursion -- shuttle provided)
6:00pm - 6:30pm Busses leave from Hotel to Disney Springs (Meet at Convention Center Entrance. Bus #1 leaves at 6:00pm, Bus #2 leaves at 6:30pm)
9:00pm - 9:30pm Busses leave from Disney Springs to Hotel (Bus #1 leaves at 9:00pm, Bus #2 leaves at 9:30pm)
Wednesday, September 25, 2019
7:30am - 8:30am Morning Refreshments in Majestic Palm EFG
7:30am - 5:30pm Registration Open
7:30am - 3:00pm Posters on Display
Session 5 [8:30am - 10:00am]
Session Title Osteoporosis Drugs: Morphometry to Mechanism
Moderator Matthew R. Allen, Indiana University School of Medicine, Indianapolis, IN, USA
8:30am David W. Dempster, Helen Hayes Hospital, West Haverstraw, NY, USA
Cellular and Tissue Level Actions of Osteoporosis Medicines
9:00am Joshua F. Yarrow, Malcolm Randall VA Medical Center, Gainesville, FL, USA
Bodyweight-Supported Treadmill Training and Passive Cycle Training Produce Differential Effects on Cancellous Bone Loss in Spinal Cord Injured Rats
9:15am Samantha Costa,Maine Medical Center Research Institute, Scarborough, ME, USA
Inverse Correlation Between Trabecular Bone Volume and Bone Marrow Adipose Tissue in Rats Treated with Osteoanabolic Agents
9:30am Elizabeth A. Swallow, Indiana University School of Medicine, Indianapolis, IN, USA
Treatment-Induced Cortical Porosity Infilling in an Animal Model of Progressive Chronic Kidney Disease
9:45am Kelsey Carpenter, Rush University Medical Center, Chicago, IL, USA
Sclerostin Antibody Rescues Hypophosphatemia and Increases Bone Mass in Hyp Mouse Model
10:00am - 10:30am Refreshment Break and Networking in Majestic Palm EFG
Session 6 [10:30am - 12 noon]
Session Title Osteocyte Morphometry in Physiology, Pathology, and Intervention
Moderator Sarah L. Dallas, University of Missouri Kansas City, Kansas City, MO, USA
10:30am Richard Weinkamer, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany
Quantitative Description of the Osteocyte Lacunocanalicular Network and Beyond
11:00am Natalie A. Sims, St. Vincent's Institute of Medical Research, Melbourne, Australia
MicroCT OTSU-Thresholding During Cortical Bone Development and the Role of Osteocyte-Derived GP130 and SOCS3
11:15am Elliott Goff, ETH, Zurich, Switzerland
Ultra-High-Resolution Micro-CT Imaging and High-Throughput Phenotyping of Individual Osteocyte Lacunae in Human Bone
11:30am Jennifer C. Coulombe, University of Colorado, Boulder, CO, USA
3D Peri-Lacunar Bone Mineral Density Changes with Oblateness
11:45am Xiao-Hua Qin, ETH, Zurich, Switzerland
3D-Printed Mini Bone Organs: An In Vitro Model to Study and Manipulate Osteocyte Morphology in Three Dimensions
12 noon - 1:30pm Lunch and Poster Viewing
(Poster Presenters are to be stationed at their poster displays from 12:45pm - 1:30pm)
Session 7 [1:30pm - 3:00pm]
Session Title Intravital Imaging of Bone and Bone Cancer
Moderator Ralph Mueller, ETH, Zurich, Switzerland
1:30pm Michelle M. McDonald, Garvan Institute of Medical Research, Sydney, Australia
Intravital Imaging of the Tumour Bone Niche Reveals Novel Cell Behavior: Implications for Microenvironmental Regulation of Tumour Cell Dormancy
2:00pm Donald B. Kimmel, University of Florida, Gainesville, FL, USA
Inhibition of Vascular Endothelial Growth Factor Causes Low Bone Blood Flow, Bone Strength, and Bone Hydration With No Effect on Bone Mass and Microarchitecture
2:15pm J. Ignacio Aguirre, University of Florida, Gainesville, FL, USA
Vascular Endothelial Growth Factor Antibody (Anti-VEGF) Monotherapy Causes Destructive Advanced Periodontitis but Not Osteonecrosis of the Jaw in Rice Rats (Oryzomys palustris)
2:30pm Evelyn J. Castillo, University of Florida, Gainesville, FL, USA
Preventing Periodontitis or Controlling its Progression Dramatically Reduces the Development of Bisphosphonate-Related Osteonecrosis of the Jaw in Rice Rats (Oryzomys palustris)
2:45pm Katherine R. Barratt, University of South Australia, Adelaide, Australia
Raising Serum 25-Hydroxyvitamin D Levels Improves Bone Volume and Mineral Density in Hyp Mice
3:00pm - 3:30pm Refreshment Break — Poster Presenters and Sponsors to Remove Displays
Session 8 [3:30pm - 5:00pm]
Session Title Lineage Tracing of Bone Cells
Moderator Natalie A. Sims, St. Vincent's Institute of Medical Research, Melbourne, Australia
3:30pm Ivo Kalajzic, University of Connecticut Health Center, Farmington, CT, USA
Lineage Tracing in Bone
4:00pm Sara H. Windahl, Karolinska Institutet, Huddinge, Sweden
αSMA Osteoprogenitor Cells Contribute to the Increase in Osteoblast Numbers in Response to Mechanical Loading
4:15pm Reinhold G. Erben, University of Veterinary Medicine, Vienna, Austria
Harnessing the Power of Laser Capture Microdissection for In Situ Gene Expression Analysis in Bone Cells
4:30pm Anders Palmquist, University of Gothenburg, Gothenburg, Sweden
The Hierarchical Nature of Osseointegration: Multiscale and Multimodal Assessment of the Bone-Implant Interface
4:45pm Phil Salmon, Bruker MicroCT, Kontich, Belgium
The Linear Decline of Cross-Sectional Trabecular Fractal Dimension Downstream of the Growth Plate Indicates Uniform Modeling Dynamics in the Murine Metaphysis and Provides New Morphometric Indices Linked to Emergent Pattern
5:00pm Sessions Conclude for the Day
5:45pm Busses begin boarding at Hotel Convention Center Entrance at 5:45PM and leave promptly at 6:00PM for SeaWorld Orlando
6:30pm - 9:30pm Dinner Banquet at Sharks Underwater Grille SeaWorld Orlando
Thursday, September 26, 2019
7:30am - 8:30am Morning Refreshments in in Majestic Palm EFG
7:30am - 11:30am Registration Open
Session 9 [8:30am - 11:30am]
8:30am - 9:30am

General Session: Practical Bone Histomorphometry in Rodents
Thomas J. Wronski and Reinhold G. Erben

Session Title Practical Training in Bone Methodology
9:30am - 11:30am

Pre-assigned groups will rotate between sessions below

Sectioning Bone Samples with a Microtome

Identification of Bone Cells in Histologic Sections

MicroCT Imaging of Bone Samples I

MicroCT Imaging of Bone Samples II

11:30am Conference Concludes

The mission of the International Society of Bone Morphometry is to establish quality standards in bone morphometry as an essential research tool and to promote the dissemination of new knowledge, technological advances, and approaches to bone morphometry. To learn more about the International Society of Bone Morphometry (ISBM), feel free to visit their website at www.bonemorphometry.org

The University of Florida’s Institute of Food and Agricultural Sciences (UF/IFAS) is a federal-state-county partnership dedicated to developing knowledge in agriculture, human and natural resources, and the life sciences, and enhancing and sustaining the quality of human life.

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